Monthly Archives: March 2017

PacBio Sequel Version 2 Chemistry and new Iso-Seq Protocol

PacBio Sequel Version 2 Chemistry   We have recently beta-tested the new PacBio Sequel chemistry (V2).  The tests have demonstrated significant yield and read-length improvements.  All current and future Sequel runs will be carried out with the new chemistry.  In

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  • Genome assemblies from single nuclei of unculturable fungi and other microbes. Combining WGA, Illumina data from in… ,
  • New way to index micro-well plate based scRNA-seq libraries by exposing nuclei to barcoded poly-A oligos (before Sc… ,
  • Transposons help perpetuate conserved higher-order chromosomal structures ,
  • Mitochondria in the blood stream? Amazing how abundant particles can escape us for ages. "We estimate that there ar… ,
  • Off-topic, but amazing out-of-the-box thinking -- Cyanobacteria used to create "living bricks": "DARPA-backed livi… ,